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Perfluoroelastomers and Other Specialty Elastomers

Dia•Com's International Corporate Headquarters was specifically designed and constructed for state-of-the-art molded elastomeric diaphragm design and manufacturing. The 30,000 square foot facility, completed during the spring of 1994, had detailed planning and consideration given to material flow, HVAC and electrical systems as well as future expansion.

Dia•Com building exterior

Microprocessor-Controlled Production Presses

Microprocessor-Controlled Production Presses were designed specifically for the production of fabric-reinforced and homogeneous elastomeric diaphragms. Our new production presses are built with high strength components. The microprocessors closely control the vulcanization process, thus assuring precise, repeatable control of the molding process. The result is high quality, low cost diaphragm production. Dia•Com utilizes unique compression and transfer molding processes to maximize efficiencies and insure the dimensional integrity of each part.

Dia•Com floor 3 production

Dia.Com Has Been Certified to ISO/ TS 16949

Dia.Com's Quality Systems are certified to the ISO/ TS 16949:2002 Quality Management System, an International standard developed to supersede the QS-9000 Quality System. ISO/ TS 16949:2002 uses a process approach when developing, implementing, and improving the effectiveness of a quality management system, to enhance customer satisfaction by meeting customer requirements.

History

Dia•Com is a leading international provider of innovative, cost-effective molded diaphragm solutions critical to the operation of essential systems and equipment in industrial, automotive, aerospace, medical instrumentation, and food and water processing applications. The company's reputation for excellence is based on superior quality in the design, manufacture and application of its high-performance, state-of-the-art, fabric-reinforced and homogeneous elastomeric diaphragm seals.

The company was founded in 1983 as a supplier of custom and standard diaphragm seals known for reliability and dependability. Today, Dia•Com, with worldwide corporate headquarters in Amherst, New Hampshire, focuses on forming strategic customer partnerships critical to the development of unique, technologically superior design solutions linked to its customers' success. As an extension of its customers’ design teams, Dia•Com offers a broad range of custom diaphragm solutions that are “designed for manufacturing,” and as a result, are more comprehensive, robust and cost-effective than competitive products.

A novel perfluoroelastomer seeded with adipose-derived stem cells for soft-tissue repair.

Clavijo-Alvarez JA, Rubin JP, Bennett J, Nguyen VT, Dudas J, Underwood C, Marra KG.

Source: http://www.ncbi.nlm.nih.gov/pubmed/17016179

Source

Division of Plastic and Reconstructive Surgery and Department of Bioengineering, University of Pittsburgh, USA.

Abstract

BACKGROUND:

There is a need for engineered soft tissue in reconstructive surgery, particularly after tumor removal. An ideal implant that will provide structural support and a favorable environment for growing cells is a key element in the process of tissue engineering. Nonbiodegradable materials that become well incorporated within the new tissue are a good solution, but many such materials do not have a surface favorable for cell adherence and proliferation. The authors hypothesized that the modification of the pore size in a novel fluoropolymer would improve the adherence and enhance the proliferation of adipose-derived stem cells.

METHODS:

Fluoropolymers with two varying pore size ranges were examined. Fluoropolymer compound U48 (pore size, 100 to 180 microm) and fluoropolymer compound P54 (pore size, 10 to 55 microm) were seeded with human adipose-derived stem cells, and cell adherence to the material was measured after 4 hours and cell proliferation was measured after 72 hours. Cell-seeded constructs were implanted subcutaneously in a nude mouse model for 30 days.

RESULTS:

Fluoropolymer surface treatment with fibronectin improved the attachment of adipose-derived stem cells to the well plates but did not improve attachment to the fluoropolymer, regardless of pore size. Fluoropolymer U48 increases the adherence and provides a favorable surface for proliferation of adipose-derived stem cells.

CONCLUSIONS:

After subcutaneous implantation into nude mice, tissue growth was observed in the fluoropolymer samples with the larger pore size. The characteristics of this new material will allow for future clinical applications in plastic and reconstructive surgery.

PMID:
17016179
[PubMed - indexed for MEDLINE]

 

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