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Perfluoroelastomers and Other Specialty Elastomers
DiaCom's
International Corporate Headquarters was specifically
designed and constructed for state-of-the-art molded elastomeric
diaphragm design and manufacturing. The 30,000 square
foot facility, completed during the spring of 1994, had
detailed planning and consideration given to material
flow, HVAC and electrical systems as well as future expansion.
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Microprocessor-Controlled Production
Presses
Microprocessor-Controlled
Production Presses were designed specifically for the
production of fabric-reinforced and homogeneous elastomeric
diaphragms. Our new production presses are built with
high strength components. The microprocessors closely
control the vulcanization process, thus assuring precise,
repeatable control of the molding process. The result
is high quality, low cost diaphragm production. DiaCom
utilizes unique compression and transfer molding processes
to maximize efficiencies and insure the dimensional integrity
of each part.
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Dia.Com Has Been Certified to ISO/ TS 16949
Dia.Com's Quality Systems are certified to the ISO/ TS 16949:2002 Quality Management System, an International standard developed to supersede the QS-9000 Quality System. ISO/ TS 16949:2002 uses a process approach when developing, implementing, and improving the effectiveness of a quality management system, to enhance customer satisfaction by meeting customer requirements.
History
DiaCom
is a leading international provider of innovative, cost-effective
molded diaphragm solutions critical to the operation of essential
systems and equipment in industrial, automotive, aerospace,
medical instrumentation, and food and water processing applications.
The company's reputation for excellence is based on superior
quality in the design, manufacture and application of its
high-performance, state-of-the-art, fabric-reinforced and
homogeneous elastomeric diaphragm seals.
The company was founded in 1983 as a supplier of custom and
standard diaphragm seals known for reliability and dependability.
Today, DiaCom, with worldwide corporate headquarters
in Amherst, New Hampshire, focuses on forming strategic customer
partnerships critical to the development of unique, technologically
superior design solutions linked to its customers' success.
As an extension of its customers design teams, DiaCom
offers a broad range of custom diaphragm solutions that are
designed for manufacturing, and as a result, are
more comprehensive, robust and cost-effective than competitive
products.
A novel perfluoroelastomer seeded with adipose-derived stem cells for soft-tissue repair.
Source
Division of Plastic and Reconstructive Surgery and Department of Bioengineering, University of Pittsburgh, USA.
Abstract
BACKGROUND:
There is a need for engineered soft tissue in reconstructive surgery, particularly after tumor removal. An ideal implant that will provide structural support and a favorable environment for growing cells is a key element in the process of tissue engineering. Nonbiodegradable materials that become well incorporated within the new tissue are a good solution, but many such materials do not have a surface favorable for cell adherence and proliferation. The authors hypothesized that the modification of the pore size in a novel fluoropolymer would improve the adherence and enhance the proliferation of adipose-derived stem cells.
METHODS:
Fluoropolymers with two varying pore size ranges were examined. Fluoropolymer compound U48 (pore size, 100 to 180 microm) and fluoropolymer compound P54 (pore size, 10 to 55 microm) were seeded with human adipose-derived stem cells, and cell adherence to the material was measured after 4 hours and cell proliferation was measured after 72 hours. Cell-seeded constructs were implanted subcutaneously in a nude mouse model for 30 days.
RESULTS:
Fluoropolymer surface treatment with fibronectin improved the attachment of adipose-derived stem cells to the well plates but did not improve attachment to the fluoropolymer, regardless of pore size. Fluoropolymer U48 increases the adherence and provides a favorable surface for proliferation of adipose-derived stem cells.
CONCLUSIONS:
After subcutaneous implantation into nude mice, tissue growth was observed in the fluoropolymer samples with the larger pore size. The characteristics of this new material will allow for future clinical applications in plastic and reconstructive surgery.
- PMID:
- 17016179
- [PubMed - indexed for MEDLINE]
Publication Types
MeSH Terms
Substances
- diaphragms - diaphragm seals - fabric reinforced diaphragms - rolling diaphragms - molded elastomer diaphragms - molded rubber diaphragms - Sitemap - Web Designers
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